Scope: The aim of a Device Profile is to provide an independent perspective on the objective assessments of specific devices in development or clinical use to help inform clinical practice. Ideally, the review should encompass all aspects of the product, including basic technology, with the primary focus on the clinical work and post-marketing findings. Using the literature reviewed, the authors are encouraged to provide a critical appraisal of the most important and up-to-date information and discuss how the technology is likely to impact on the management of specific diseases.
Focus: Authors should restrict their discussion to licensed indications and it is recommended that national/regional regulatory product guidelines are followed, particularly in terms of indications and dosage. When a device is discussed outside of its approved license, readers should be made aware of this fact in the first instance.
For investigational devices not yet licensed for any indication, the manuscript should make reference to this from the outset.
Word limit: The word limit for Device Profiles is 3,000-7,000 words (not including tables, figures and references).
Timing: Several factors contribute to the selection of devices and technologies to be reviewed, including scientific need, emergence of new important clinical data, market launches/approval of new indications, and the requirement for an alternative appraisal of the literature. Thus timing is critical and it is important that the deadlines set by the Commissioning Editor are met. However, if you feel there is a need to delay publication, for instance to discuss new data presented at a scientific meeting or to coincide with the publication of primary literature, the Commissioning Editor will be happy to accommodate such requests.
Every article must contain:
Title: Should be concise but informative, including the drug and therapeutic indication. Titles should not contain brand names
Authors’ names and addresses: Including address, academic qualifications and job titles of all authors, as well as telephone number, fax number and email address of the author for correspondence on a separate cover sheet as the peer reviewers will be blinded to the authors’ identity. Please note that only the address of the first author of the article will appear on Medline/PubMed, not necessarily the corresponding author.
Summary (maximum 150 words): The role of the summary is to draw in the interested casual browser. This should not be an abstract but should outline the article scope and briefly put it into context. No references should be cited in the summary.
- Keywords: A brief list of keywords, in alphabetical order, is required to assist indexers in cross-referencing. The keywords will encompass the therapeutic area, mechanism(s) of action, key compounds etc.
Introduction: Incorporating basic information on disease incidence and prevalence, unmet medical need and present treatment guidelines (highlighting regional variations where appropriate).
Body of the article:
- Overview of the market:
- What are the unmet needs of currently available devices/technologies?
- Introduction to the device:
- How the device works
- Cost-effectiveness (training, waste disposal, equipment required)
- Sensitivity and specificity
- Clinical profile and post-marketing findings:
- Phase I, II and III data
- Alternative devices:
- A standalone box, summarizing competing technologies in the field.
- How the technology fits into the field of medical devices:
- Include information on the status of the device, i.e., where it is currently approved, in which countries it is approved and for what indications. This should cover Europe, US and rest of the world where appropriate.
- Conclusion: An analysis of the data presented in the review.
Expert commentary: To distinguish reviews published in the series of journals, authors must provide an additional section entitled Expert commentary. This section affords authors the opportunity to go beyond the conclusion and provide their interpretation of the data presented in the article, discussing any improvements the drug has over currently available therapies and how likely physicians are to convert to treatment with the drug. In addition there is the opportunity to discuss the developments that are likely to be important in the future and the avenues of research likely to become exciting as further studies yield more detailed results (i.e. what are the prospects for combination therapies?).
Five-year view: Authors are challenged to include a speculative viewpoint on how the field will have evolved 5 years from the point at which the review was written.
Key issues: An executive summary of the authors’ main points (bulleted) is very useful for time-constrained readers requiring a rapidly accessible overview.
Information resources: A brief summary to direct the reader to the most important further reading, related articles and relevant websites.
Important references should be highlighted with a one/two star system and brief annotations should be given (see the journal Information for Authors page for examples and for a more detailed description of our referencing style).