Research should be communicated in a way that supports verification and reproducibility, and as such we encourage authors to provide comprehensive descriptions of their research rationale, protocol, methodology, and analysis.
To support clear and comprehensive communication of research, a number of study-design specific consensus-based reporting guidelines have been developed. We recommend authors to use these as guidance prior to submitting their manuscript.
STRENDA guidelines for reporting of enzymology data
STROBE guidelines for observational studies in epidemiology (including extensions)
Full information on the statistical methods and measures used in the research must be included within the manuscript. Authors are encouraged to consult the SAMPL guidelines. Manuscripts may be sent for specialist statistical review if considered necessary.
Cell line authentication
Due to concerns regarding cross-contamination and misidentification, if human cell lines are used in a study, authors are strongly encouraged to include the following information in their manuscript:
Source of the cell line, including when and from where it was obtained.
Whether the cell line has recently been authenticated and by what method.
Whether the cell line has recently been tested for mycoplasma contamination.
Gene nomenclature and reporting of sequence variants and phenotypes
Standardized gene nomenclature should be used throughout the manuscript. Human gene symbols and names can be found in the HUGO Gene Nomenclature Committee (HGNC) database. Alternative gene aliases that are commonly used may also be reported but should not be used alone in place of the HGNC symbol.